[HTML][HTML] Genetics of the Lp (a)/apo (a) system in an autochthonous Black African population from the Gabon
K Schmidt, HG Kraft, W Parson… - European journal of human …, 2006 - nature.com
Abstract Plasma lipoprotein (a)(Lp (a)) is a quantitative trait associated with atherothrombotic
disease in European and Asian populations. Lp (a) concentrations vary widely within and
between populations, with Africans exhibiting on average two-to threefold higher Lp (a)
levels and a different distribution compared to Europeans. The apo (a) gene locus on
chromosome 6q26–27 (LPA, MIM 152200) has been identified as the major quantitative trait
locus (QTL) for Lp (a) concentrations in Europeans and populations of African descent …
disease in European and Asian populations. Lp (a) concentrations vary widely within and
between populations, with Africans exhibiting on average two-to threefold higher Lp (a)
levels and a different distribution compared to Europeans. The apo (a) gene locus on
chromosome 6q26–27 (LPA, MIM 152200) has been identified as the major quantitative trait
locus (QTL) for Lp (a) concentrations in Europeans and populations of African descent …
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